Abstract This is experimental study was done in Clinic of ultrasound, Alfao, Algadarif state, Sudan, during the period from June to October 2018, using Sonoscape A6machine with Curvilinear transducer 3.5MHZ to measure the normal spleen dimensions in adult Sudanese, and to correlate these dimensions with the variables of age, gender, height, weight and body mass index, the study was done with the subjects lying in right lateral decubits in deep breath the spleen dimensions were measured by centimeter. A number of 50 subjects age( 20- 70years).male 20 (40%)and female30 (60%) were examined using ultrasound ,the mean values for body characteristic age, height ,weight and BMI are37.80± 14.8,168.2±8.8 ,60.8±11.04 ,21.3±2.6 respectively the study found The mean value of spleen Length ,spleen width, spleen Thickness and Splenic volume were 8.976±1.1cm ,3.9±0.6cm ,3.73±0.7cm,71.38±31.04cm3 respectively, and there was significant correlation between spleen length with height and weight and non-significant correlation with body mass index, and there was non- significant correlation between spleen width and spleen depth with height, weight and BMI, furthermore there were significant correlation between spleen volume and height and non-significant correlation with weight and BMI and there were statistically significant differences between males and females in (length) and nonsignificant differences between male and female in (depth,, width and volume) the means of (length, depth, width and volume) are, (9.565,8.583), (3.8750, 3.6333), (3.9750, 3.6333), (79.805,65.777) for Male and Female respectively , the men had larger spleen than female in relation of spleen to gender, there is non-significant correlation between spleen dimension and age.

LIST OF CONTENTS

 Topic page No

I الایھ

Dedication II

Acknowledgment III

Abstract (Arabic) IV

Abstract (English) V

List of tables VI

List of figures VII

List of abbreviations VIII

List of contents IX

CHAPTER ONE

1-1Introduction 1

1-2 Problem of study 2

1-3Objectives 2

1-3-1 General Objective 2

1-3-2 Specific Objectives 2

1-4 Over view of study 3

CHAPETR TWO

2-1.Anatomy 4

2-1-1Structure 4

2-1-2Relation 5

2-1-3Blood supply 6

2-1-4Lymphatic 6

2-1-5Variation 7

2-2 Development 8

2-3 Physiology 9

2-4 Pathology 11

2-4-1Diabetes 11

2-4-2Cystic fibrosis 12

X

2-4-3Pancreatitis 12

2-4-4Pancreatic Neoplasm 13

2-5 Pancreatic Sonographic Appearance 14

2-Background studies 16

 Chapter Three

3-1Materials 19

3-1-1Study Group 19

3-1-2 Ultrasound unit used 19

3-2Methods 19

3-2-1 Ultrasound Technique 19

3-2-2 Data collection 21

3-2-3Data analysis 21

 Chapter Four

Result 22

 Chapter Five

5-1 Discussion 33

5-2Conclusion 36

5-3 Recommendations 37

References 38

Appendices