The study was conducted under the topic, stress among health workers of Kyenjojo hospital, Kyenjojo Town council, Kyenjojo District. It was guided by the following objectives; to find out the causes of stress among health workers of Kyenjojo hospital, to find out how stress has affected the performance of health workers of Kyenjojo hospital, to find out the health workers attitudes towards the stress they experience. The methods of collecting data included questionnaires to obtain data from respondents about the causes of stress and the effects and observation was used to consolidate the findings. Findings indicated that health workers of Kyenjojo hospital are stressed and the identified causes included work overload, poor communication, roles ambiguity, and less promotional opportunities. The effects of stress included absenteeism, substance abuse and sleep disturbances, and the attitudes towards stress included lack of morale, low motivations and rudeness.