ABSTRACT

The study was conducted in Gombe local government from September-October 2014.the research was aimed at determining the effectiveness of sulphadoxine pyrimethamine in relation to malaria prevalence among pregnant women. 156 pregnant women attending antenatal clinic at some selected maternities were for used for the research. Blood samples were collected using vein puncture technique. Thick and thin films of the collected samples were prepared and stain using field stain and observe under microscope for malaria parasites. An overall prevalence of 41.67% was recorded, where study subjects in third trimester and multigravidae had the highest prevalence of 42.2% and 37.61% respectively. Prevalence in relation to SP utilization revealed that, study subjects who have taken SP recorded 55.32% as compared to35.7% from those who have not taken the drugs. Further research should be conducted using pregnant women who have the drug as direct therapy in order to assess the exact effectiveness of the drugs.

TABLE OF CONTENT

Title Page………………………………………………………………………………………….i

Declaration………………………………………………………………………………………...ii Certification………………………………………………………………………………………iii

Acknowledgement…………………………………………………………………...................iv

Abstract……………………………………………………………………………………..…….vi

TABLE OF CONTENT……………………...………………………………………………….viii

CHAPTER ONE

INTRODUCTION

1.0 Background 0f the study ……………………………….……………………………………1

Statement of the problem …………………………………………………………………………3

 Justification of the study …………………………………………………………………………3

Aim of the study……………………………………………………………………….…………..3

Objective of the study……………………………………………………………………………..3

CHAPTER TWO

 Literature Review……….………………………………………………….………………...…4

 2 .1 Life Cycle of malaria parasite …………………………………………………………..….4

 2.2 Transmission of malaria parasite ……………………………………………………….….9

2.3 Diagnosis …….…………………………………………………………………………...…10

2.4.1Prevention …………………………………………………………………………..….…10

CHAPTER THREE

MATERIAL AND METHOD

Study area ………………………………………………………………………………………11 Study population ………………………………………...………………………………………..11

3.5.1 Specimen Collections and examination procedure ………………………………………..12 3.5.2 Slides Preparation and Examination Procedures …………..……….……………………..12

3.6 Identification of the Parasite …………………………………………………………………..13

3.7 Prevalence Determination ……………...……………………………………………….…….13

3.8 Data Analysis………...………………………………………………………………….…… 13

CHAPTER FOUR

 4.0 Result ………………………………………………………………………….……………14

4.1 Demographic information of the study subject ………………………….……..……………14

4.2 Prevalence of malaria among pregnant women ……………………………………………14

CHAPTER FIVE

Discussion…………………………………..…………………………………...…………….19

Conclusion…………………………………………………………………..…………..…..…19    

RECOMMENDATION…………………………………………………..………….…………..19

.REFERENCE……………………………………………………………………………………