ABSTRACT

Several plants have been used in the treatment of various disorders without scientific basis. The present study examine the pancreatic effect of Buchholzia coriacea formulated diet in sucrose-fed pregnant rats and their offspring. Buchholzia coriacea seeds were obtained from Ogbete main market, Enugu state, identified, dried and grounded using a miller machine. 10% of the seed powder was used to formulate their diet. Thirty (240) adult female and six (6) adult male albino rats (180-250 g) were used in this study. High sucrose (20%) were given via drinking water to animals before, during and after pregnancy. Group A; Control normal was administered distilled water, group B received sucrose + 10% Buchholzia Coriacea formulated diet (BCFD), Group C; untreated rats were administered sucrose and distilled water while Group D received 10% Buchhoiza Coriacea formulated diet (BCFD) only. All animals were sacrificed following overnight fast by anaesthetic does of diethylether and cervical dislocation. Blood samples were obtained through cardiac puncture error of mean. SUC (20%) (untreated) significantly elevated blood  glucose levels (P