To assist the judgment of human operators, computer-aided drug dispensing system with adaptive and predictive control. The assisting system can predict future responses of patient to drug infusion calculate optimal inputs and present that value on a monitor. Regardless of sudden disturbance such as bleeding. Human operators of the computer-aided system were able to control arterial blood pressure.

To improve the computer-aided system. Future studies will be required to consider the method for emergency warning or correspondence to multiple drug infusions.

Keywords: Adaptive predictive control, computer-aided system, neural network, arterial blood pressure, system evaluation accomplished physicians.

1.     For example, it is difficult for beginners to appropriately grasp the characteristics of drug responses reflecting the history of past inputs and output or to respond to acute emergency such as bleeding. Therefore, the effectiveness of intelligent control system may apply to the quick decision making of experienced beginners. A computer-aided drug dispensing system using adaptive and predictive control was suggested in this study: effectiveness was evaluated in human operators. In blood pressure control using a single drug, the learning effect of the assistant system on beginners without pharmacological knowledge was investigated.