The purpose of this study was to investigate the effects of strategic responses to advances in technology on organization‟s performance: looking at the evidence from textbook publishers in Kenya. More specifically, the study sought to evaluate how Change in Recruitment processes, Human Resource Development, Customer Relations Management and organizational policy change affect organization‟s performance. To achieve the objectives of the study, a descriptive research design was adopted where all 40 Publishing firms registered under the Kenya Publishers Association were targeted. The study relied solely on primary data which was collected using structured questionnaires containing mainly closed ended questions for ease of analysis. Data analysis was done using descriptive and inferential statistics with an aid of a computer software SPSS. Multiple regression and correlation analyses were applied in the analysis of the data to determine the relationship between the variablesThe correlation results, found that there was a strong positive correlation relationship, 0.572 with significance of p = 0.00< 0.05 between human resource management and performance of publishing firms. The study further indicated a weak positive relationship, 0.349 with significance of p = 0.037