This research looks at the role of fraud management in the profitability of Nigerian banks (A study of first bank Nigeria plc). The objectives of this study include to ascertain the role of fraud detection and the contribution of fraud investigation in the profitability of Nigerian banks. Ex-post factor research design was adopted for this study because secondary data was used. Data was collected from the bank’s annual report and fact books covering from the period 2006 –2015 However regression was ran and hypothesis tested using a T-test. Findings were based on the result of the regression and one of the findings of this study is that Fraud detection plays a significant role in the profitability of Nigerian banks. One of the recommendations says that the management should employ the service of an investigator once fraud is suspected so as to detect fraud in the banking system which enhances the profitability of the system.