Abstract Condom use is of greater benefit to the youths. It is a tool that serves a great deal in prevention of HIV/AIDS and HIV related infections, so are other STD/STIs and unwanted pregnancies. Despite such benefits, youths do not use condoms. Therefore, this study aimed at assessing the KAP of youths attending KIU-TH towards condom use in Ishaka municipality, Bushenyi district. The study design was cross sectional and descriptive, but data analysis was mainly quantitative. 67 respondents were involved both male and female who were selected using a simple random sampling procedure. Knowledge of respondents was good as majority of the respondents 55 (82%) had ever heard of safer sex practices and 50 (91%) could describe safer sex practices rightly. Attitudes were poor as majority 46 (69%) had a negative attitude towards condom use. Reasons mainly given were: condoms are painful, reduce lubrication, cause sores, make sex unpleasurable. Practice was also poor as majority of respondents 42(63%) always had unsafe sex. It is recommended that the MOH should ensure that youths are equipped with adequate knowledge about condom use and in so doing; to help change the attitude of youths from being negative to positive in regard to condom use. This can be done through schedhulingmore educative programs to teach youths about the merits of safe sex. Health education talks can be done at community level, parish level or even conducted in schools (secondary schools, tertiary institutions or even universities). Parents should also come in here, to teach their children, especially those that have reached adolescent stage to always use condoms each time they want to have sex. Parents must explain to these adolescents the risks that they may face when they opt for unsafe sex.