Controversy exists about the optimal imaging modality in patients with stroke. This work was carried out to optimally compare CT and MRI images in patients with stroke. ( A case study of  National Hospital, Abuja). A retrospective study of 54 stroke patients who underwent both CT scans and MRI scans at National Hospital, Abuja between January 2010 to March 2013 was conducted. Tables and T-test for hypothesis was used to analyse the data. CT is significantly more sensitive than MRI in the detection of acute hemorrhagic stroke (92% vs. 48%  p