597 articles were reviewed, 426 did not comply with the exclusion criteria and were rejected. 171 articles were accepted as evidence. The results show an emerging evidence base for CAMBRA in support for the viability of assessing the risk factors: Saliva flow; Salivary counts of S. mutans and Lactobacilli; Frequency of fermentable carbohydrate intake; past caries experience and for the use of Dental chewing gum; Chlorhexidine; Topical fluoride; Glass ionomers; CPP/ACP for caries management.