This whole study was about an investigation of the factors responsible for girl child drop out from school in lganga district in Uganda. It had been realized that the drop out rates for girls were growing at a higher pace, which meant that the opportunities of girl child to enjoy the fruits of education were in a withering state. The general objective of the study was to determine the causative factors leading to girl child drop out from school. For such an objective to be realized, there was need for research questions to be formulated such that the findings of the study could correlate with the objectives. Chapter two had a whirl wind tour of related literature on girl child drop out from school and this was effected by citing what other scholars had written on the subject under study. The study involved a descriptive research design as this was viewed necessary for this particular study. In the process of data collection, questionnaires and interview guides were used after which data had to be scrutinized and analyzed basing on the set objectives The findings from the study revealed that girl child drop out was attributed to factors like lack of guidance and counseling, Cultural practices and traditions, uncongenial home environment and delinquent acts among others. A deduction was reached at which called for parent and teacher cooperation to offer proper guidance and conuseling to learners and the need for literacy programs to educate parents who are still seeing no value in sending their daughters to school.