Abstract The study was set to investigate Causes of Unemployment Among Youth in Mpumudde Sub County, Lyantonde District Uganda. The study was based on the following three objectives; to examine the reasons of unemployment among youth; to examine the impact of unemployment among youth and to determine the ways of solving youth unemployment in Mpumudde Sub County, Lyantonde District, Uganda. A sample of 80 respondents both females and male youth of Mpumudde Sub County, Lyantonde District were selected for the study. The study employed a cross-sectional research design and methodology used was both qualitative and quantitative. Questionnaires and documentary review were the major tools of data collection. In regard to reasons of unemployment among youth in Mpumudde Sub County, Lyantonde District, Uganda; it was found out by majority of respondents, 50% strongly disagreed that youth in the district do not know where to find a job, majority47.50% agreed that youth dislike certain jobs, majority 61.25% strongly agreed that education of youth in the district is too theoretical, majority 58.75% agreed that youth have negative attitude towards work, majority 41.25% agreed that employers employ relatives who are less qualified than others, majority 36.25% and 46.25% respectively agreed or strongly agreed that there is too much corruption.In regard to impact of unemployment among youth in Mpumudde Sub County, Lyantonde District, Uganda; it was revealed by the majority of respondents,42.5% agreed that being unemployed for a longer time leads to a lack of work experience and skills, majority57.5% agreed that unemployment among youth leads to reduced earnings, majority 45% of respondents strongly agreed that unemployment among youth leads to crime and violence amongst youth, majority 52.5% strongly agreed that unemployment among youth leads to commercial sex work, majority 50% strongly agreed that unemployment among youth leads to the spread of HIV/AIDS. In regard to ways of solving youth unemployment in Mpumudde Sub County, Lyantonde District, Uganda; it was revealed by the majority, 43.75% strongly agreed that government should create more industries, majority 33.75% strongly agreed respectively that education system to be changed from theoretical to more practical, majority43 7~% strongly agreed that youth should get a chance to get some experience in entrepreneurship, majority 3 7.5% of respondents strongly agreed that government should give training to youth and encourage them to work for their own businesses.It was recommended that;ILO member states shouldplace much emphasis on developing skills, government and other stakeholders should put up a strong accountability mechanism, education system has to be changed from theoretical to more practical.