1.0    INTRODUCTION
1.1    BACKGROUND OF THE STUDY
Over 2.1 million children under 15 years in 2009 were affected globally with HIV, 370,000 were new infections and 90% of them were in sub-Saharan Africa.  Noteworthy is the fact that 90% of these pediatric infections were through Mother to Child Transmission of the virus Owe-Larsson and Sall (2009).  The burden of Mother to Child Transmission of HIV is much higher in sub-Saharan Africa due to higher levels of heterosexual transmission, high male: female ratio, high total fertility rate and high levels of breastfeeding.  Nigeria has the largest burden in the West African sub region with about 2.98 million people living with HIV.  The children epidemic in Nigeria also followed the global trend Salamon E (2009). Estimated 220,000 children are living with HIV and 90% are from Mother to Child Transmission although a small percentage of "under 15" pediatric infection could be the result of rape or other social abuse.
The virus undergoes a complex interaction with the immune system which results in production of HIV antibodies. The time between infection and antibody development is highly variable and ranges between two weeks to six months with some studies reporting 9 months Anderson, (2013). This period often termed "the window period" or "period of seroconversion" is usually marked with non-specific symptoms or may be completely asymptomatic but with extremely high viral load, associated high vertical and horizontal transmissibility and poses the greatest challenge to HIV diagnosis in pregnancy using antibody detection techniques (Shacham E, et al 2009).  This is because; a minimum quantity of antibody in the serum is required for the test result to be reactive. This can lead to high false negative test result in newly infected pregnant women who will eventually seroconvert in the course of the pregnancy. This will amount to "missed opportunity"  if these women are not re-tested later in the pregnancy. Also, new infections can occur in pregnancy after an initial antibody screening test and depending on the gestational age, pass through seroconversion and escape detection due to the current practice of single screening test on contact irrespective of the gestational age Campbell (2013). Such women will miss the opportunity to access prevention of mother to child transmission (PMTCT) services which has been proven to reduce MTCT of HIV from as high as 30-45% to less than 2%.
Although (Campbell JC et al 2013), the single antibody test algorithm is widely employed and effective in developed countries like the USA where HIV prevalence is low;  the same may not be true in a developing country like Nigeria with high HIV prevalence and large population. It may not be out of place therefore to consider the Center for Disease Controls (CDC) recommendation of a double antibody test algorithm (one in early pregnancy and a repeat in late pregnancy) to minimize false negatives and missed opportunities for diagnosis and PMTCT interventions.
 The study was carried out over one month. The total number of antenatal attendees for the period was 50.

1.2    STATEMENT OF THE PROBLEMS
Women who have HIV should talk to their HIV specialist and an obstetrician before trying to become pregnant. Some HIV medications are not safe to take during pregnancy, and it may be necessary to switch before trying to conceive. It is also important to take your HIV medications regularly. Women who have complete viral suppression (no virus detected in their blood) have a much lower risk of passing HIV to their baby than women who have virus detected in their blood. A number of studies have been done to better understand how HIV infection and HIV treatment affect the health of women and infants. Pregnancy does not appear to worsen HIV or increase the risk of death from HIV. It is not clear if HIV or HIV treatments increase the risk of pregnancy complications, such as prematurity, low birth weight, and stillbirth. However, it is very clear that certain HIV medications, such as zidovudine (ZDV or AZT) and other medications that cross the placenta, can significantly reduce the risk that the infant will become infected with HIV when the medication is taken during pregnancy and labor, and then given to the infant after delivery. That is why HIV treatment guidelines strongly recommend a combination of medications to prevent the transmission of HIV to an infant from an HIV-infected mother. Over half the respondents (58%) said that living with HIV had no impact on their working life at the moment. Seventy per cent of gay men living with HIV had taken no HIV-related sickness days in the last 12 months, and took no more sick days than HIV-negative men. Only a third had made any changes to their working lives because of their HIV status, with the most common change being alterations to working hours.
On the other hand, initial diagnosis of HIV was a time when many respondents did report an impact on their working life. Forty-two per cent reported stress or anxiety, 32% needed some time off, and 28% were very tired. However, it is important to note that almost a third of respondents said that their initial diagnosis had no impact on their working life. There was some suggestion from focus group discussions that starting or changing medication was another ‘flash point’ when HIV had an impact on their working lives.


1.3    Aims and objective
     To create awareness for the women attending antenatal at Otto Ijanikin Primary Health Centre Ijanikin, Lagos State about dangers of HIV in pregnancy.
     To identify the number of case of HIV in pregnancy in Otto Ijanikin Primary Health Centre, Ijanikin, Lagos State.
     To determine the prevalence rate of HIV in pregnancy in Otto Ijanikin Primary Health Centre, Ijanikin, Lagos State.

1.4    Significance of the study
o    The study is of great important to investigate the methods of prevalence of HIV in pregnancy women attending antenatal at Otto Ijanikin Primary Health Centre, Ijanikin, Lagos State.
o    The information ascertain from the study will guide as regards to save live of pregnant women through the prevalence of HIV in pregnancy women attending antenatal at Otto Ijanikin Primary Health Centre, Ijanikin, Lagos State.
o    The study of the work will expose the predisposing factors and control measures for HIV attack and the awareness will be very important to the pregnant women attending  antenatal at Ijanikin, Lagos State. This is because it will help them to take a adequate precautions of preventing HIV.

1.5    Scope of the study
This research work is limited to Lagos and its environments. The scope on the other hand covers the pregnant women of Ijanikin and the effect of HIV on them, especially those of the Otto Ijanikin Primary Health Central, Ijanikin, Lagos State.

1.6    Limitations of the study
The study did not differentiate between true sero-conversion and new infections in the index pregnancy. Also, this was a hospital based study done in a center of excellence for HIV services. A multi-center st