The prevalence of viral hepatitis B among patients in National Orthopedic Hospital Enugu was studied. The samples comprised that of men , woman and children 200 in numbers, all patient of orthopedic Hospital Enugu. Laboratory investigation done were this HBs  tested which 110 patient out of the 200 patients tested positive,  and liver function tests found abnormal in almost all the patients that tested positive to HBsAG routine test. The commonest clinical presentations were fever and jaundice seen in Jo patient out of the 110 patients. The infection was  highest amongst young adult 21-30 years of age. This accounted for 17.5% of the positive patients population it was lowest amongst children 1-10 and old people 60-70 which  made up 5% of the infected population. The study also gave the general view of the group of individual affected whether children or adult, and the wid expired of the repetitious B. Hepatitis B one of the major cause of human suffering in the world despite a though understanding of its transmission and prevention and control by use of vaccine was found to be prevalent in National Orthopedic Hospital Enugu among the patients. 

Title page

Certification

Dedication

Acknowledgement

Abstract

Table of contents

CHAPTER ONE 

Introduction 

1.1 introduction to hepatitis b

1.2 Purpose of study 

1.3 Significant  of study 

1.4 Statement of problem 

1.5 Limitation of study 

1.6 Hypothesis 

CHAPTER TWO

Literature review 

2.1 Structure of hepatitis b virus 

2.2 The genome and its organization 

2.3 Taxonomy of the hepatitis b virus 

2.4 Reproduction (repcication) of hepatitis bb  virus 

2.5 Origin of the term “ Australian aborigine”.

2.6 Mode of transmission of hepatitis b 

2.7 Hbv and cell damage (Cytopathic effects) 

2.8 Hepatitis b virus and hepatocellular, carcin0ns 

2.9 Hepatitis b virus infection: acute and chronic

2.10Prevention and control 

2.11Site of injection for vaccination 

2.12People at risk of contacting the virus 

CHAPTER THREE 

3.1 materials used 

3.2 Test for the presence of hepatitis b and 

3.3 Principle for the above test 

3.4 Serum bilirubin 

3.5 Principle for the test above 

CHAPTER FOUR

Result 

CHAPTER FIVE

5.1 discussion and conclusion 

5.2 Conclusion 

5.3 Recommendation 

References